Flax for Health

This ancient grain is a good source of omega-3 essential fatty acid Alpha Linolenic Acid (ALA), dietary fiber and lignans. Ancient records show that the human race has consumed flaxseed since the beginning of civilization. Today, scientific findings are confirming the nutritional benefits of including flaxseed in a balanced diet.

Flaxseed offers:

  • A high content of Alpha Linolenic Acid (ALA).  ALA is an essential fatty acid that is converted in the body to EPA and DHA, two compounds recognized for their benefits in heart health, arthritis, thrombotic disease, and brain function.  ALA also has many benefits independent of EPA and DHA.  ALA is useful in heart disease, improving immune function, cancer prevention, and male infertility.
  • Large quantities of soluble and insoluble dietary fibre, which helps increase laxation.
  • The highest plant source of lignans, which are strong antioxidants that could reduce the aging process and protect against some environmental toxins. Lignans may help reduce the risk of certain forms of cancer, particularly cancers of the breast and colon.

Flaxseed as a source of “good” fats

Flaxseed oil is a remarkably good source of Alpha Linolenic Acid  (ALA). ALA is an essential fatty acid and is one of the essential nutrients that is necessary for life.  ALA must be obtained from the diet — the human body is not able to manufacture it.

Approximately 20% of the ALA we consume is transformed in our bodies into two other fatty acids: EPA and DHA (these are the same beneficial compounds found in fish oil). The benefits of EPA and DHA include: protection from fatal heart attack, decreased inflammation and pain in arthritis, and protecting from thrombotic disease.

As well, DHA alone is noted for its effects on brain function, mood and behavior. DHA is one of the building blocks for brain growth and development. Numerous animal studies show that DHA improves learning, vision processes, memory, and concentration.2 In a Rotterdam study with humans, researchers found that elderly men who consumed more DHA were able to better sustain their mental abilities-including memory, concentration, and ability to communicate verbally.

In a Japanese study, students who took supplemental DHA were able to keep their aggression in much better control than those in the placebo group.

Due to the benefits of EPA and DHA produced from ALA in the diet, flaxseed consumption may be particularly important for vegetarians and people who prefer not to eat fish often.

In the past, most research on ALA has related to its role in producing EPA and DHA. Research in recent years, however, has brought evidence that ALA has other beneficial functions in the human body beyond its conversion to EPA and DHA — ALA is useful in protecting against heart diseases, improving immune function, and improving male infertility.

Heart diseases

A growing body of research clearly shows that flaxseed is a beneficial dietary supplement for people who want to reduce their risk of heart attack and atherosclerosis and maintain a healthy level of blood cholesterol.

Heart attack:  Population studies suggest that a diet rich in ALA protects against heart attack. Animal studies show that ALA can also reduce the occurrence of malignant heart arrhythmia such as ventricular fibrillation or ventricular tachycardia. Furthermore, dietary ALA can prolong the lives of those who have already experienced a heart attack. This was evidenced in a recent North American study of more than 76,000 nurses whose dietary habits were followed for more than 10 years.

It was also evident in a seven country study which showed the population on the island of Crete had a longer life span and a lower cardiovascular mortality rate than other populations. Their good health was partly attributed to their diet, which was high in ALA. A study in France found that recent heart-attack victims that followed the Cretan diet saw their mortality rate fall by more than 70%.

Atherosclerosis: Multiple studies have well documented the role of ALA in the prevention of atherosclerosis, which is the underlying cause of many cardiovascular diseases, including heart attacks. It has been found that the addition of ALA to the diets of hypertensive rats significantly extends their life span due to the inhibition of the growth of atherosclerotic plaque in their blood vessels.

Cholesterol: Researchers at the University of Toronto found that total blood cholesterol levels dropped by 9% and LDL decreased by 18% when a group of 9 healthy women added flaxseed to their regular diets. The women ate 50 g of milled flaxseed as day (as milled flaxseed or cooked into bread) for four weeks. High total cholesterol and LDL-cholesterol (“bad” cholesterol) levels are considered to be risk factors for atherosclerosis.

In another similar study, 10 young, healthy men and women ate flaxseed muffins providing 50 g of flaxseed per day for four weeks. Total plasma cholesterol was reduced 6% and LDL-cholesterol was reduced up to 8%. Plasma HDL-cholesterol and triglycerides did not change.

Lastly, a group of researchers conducted a three-month clinical trial studying the effects of flaxseed consumption on a group of 15 hyperlipemic men and women. The patients, who were on long-term intake of vitamin E, added three slices of flaxseed containing bread and 15 g of ground flaxseed to their daily diets. The result was a significant reduction in cholesterol levels-total blood cholesterol was reduced by 7% and LDL cholesterol levels were reduced by 11%. HDL cholesterol levels did not change during flax seed consumption.

Improved immune function

Immunity is the body’s ability to defend itself successfully against foreign substances.  Flaxseed contains two components that may improve immune function:  Alpha Linolenic Acid and lignans.  Recent research suggests that ALA and lignans in flaxseed modulate the immune response and may play a beneficial role in the clinical management of autoimmune diseases.

For example, some researchers believe that flaxseed is a potential treatment for lupus nephritis after the results of a 1995 study of 9 patients. Patients started with 15 g of flaxseed daily for four weeks. The dosage was increased to 30 g daily for the next four weeks and 45 g daily for the last four weeks. The researchers concluded that 30 g flaxseed a day was well tolerated and conferred benefit in terms of kidney function as well as inflammatory and atherogenic mechanisms important in the pathogenesis of lupus nephritis.

Flaxseed may also be useful in the nutritional management of other disorders in which the immune system becomes overstimulated, such as rheumatoid arthritis, psoriasis, and multiple sclerosis.

Cancer prevention

Flaxseed contains abundant amounts of lignans and the essential fat Alpha Linoleic Acid. These compounds have been shown to have anti-cancer effects in animals. Flaxseed appears to protect against certain cancers in humans, particularly hormone-sensitive cancers such as those of the breast, endometrium and prostate. Long-term studies of the effects of flaxseed in women with breast cancer are underway.

Male Infertility

Deficiency of DHA in sperm cells is one of the markers of sub-fertility in men.  A Belgian study demonstrated that ALA can pass through the blood-testis barrier and correct the deficiency of DHA in sub-fertile men. Interestingly, fish oil supplementation did not achieve a similar effect, showing again that ALA has its own unique properties not matched by EPA and DHA from fish oil.

Relief from constipation: flaxseed fiber

Flaxseed, like cereals and legumes, has the potential to increase laxation because it provides dietary fiber in 100 g of dry flaxseed. This can be especially important for the elderly, who often have chronic difficulties with laxation due to inactivity, low-fibre diets, and/or use of medication for other conditions. In a study of seven subjects whose average age was 78 years, the daily frequency of bowel movements and the number of consecutive days with bowel movements increased among subjects who complied with the dietary regimen of eating 50 g of flaxseed daily. The flaxseed was provided in muffins and consumed for a period of four weeks.

Flaxseed as a source of lignans

Flaxseed is the richest plant source of lignans, which are strong antioxidants that could reduce the aging process and protect against some environmental toxins. Several animal studies have shown that lignans from flaxseed reduce cancer tumours. It is likely that lignans also play a role in lowering blood cholesterol.

Since lignans are digested into estrogenic compounds, many of the health benefits of lignans may be attributable to their hormonal effects. Other benefits are derived from their non-hormonal metabolic properties such as influence on enzymes, protein synthesis or cellular transport.

 Adding flax and flaxseed oil to your diet

Flaxseed comes in many forms.  It is available whole, milled, or as an oil in bottles or capsules. Whole and milled flaxseeds may be used in cooking and baking, while the oil is useful for daily supplementation. Whole flaxseed can not be very well digested-flaxseed are hard to crack even with careful chewing-therefore consumption of the whole flaxseed releases only a small percentage of its available nutrients. One to two tablespoons of milled flaxseed a day (approximately 30 g) may provide adequate supplementation of ALA and lignans.  Organic flax oil contains some beneficial lignans while refined flaxseed oil does not. The American recommendation for adequate intake (AI) of dietary ALA for adults is 2.22 grams/day — approximately 4 grams of flaxseed oil.

The light, nutty taste of flax seed enhances the flavor of food, and adds nutritional value to your diet. Flax seed may be eaten on its own, sprinkled on cereal, popcorn, and salads, or added to oatmeal, yogurt and blender drinks. Adding flax seed to baked goods adds flavor, extra texture, and good nutrition. Milled flaxseed may be baked into a variety of products including breads, pancakes, bagels, muffins and cookies.  Although cooking does not destroy the lignans in the milled flax seed, flax oil should not be used for frying as the high temperatures will denature the healthy fats.

But be aware, not all flax products are the same. Be sure to look for a brand that is certified organic. If you opt for oil or capsules, make sure the oil is expeller pressed (also called “cold pressed”). Expeller pressed seeds produce the highest quality flax oils. But most importantly, look for the lignans. Milled flax is by far your best source of lignans, but if you prefer oil or capsules, the bottle should state “with lignans” clearly on the label.

 

References:

  1. Flax Council of Canada, 1999.
  2. Okiniwa Y. et al. A high linolenate and high alpha-linolenate diet induced changes in learning behaviour of rats. Effects of shift in diets and reversal of training stimuli. Biological and Pharmaceutical Bulliten, 19(4): 536-40, 1996
  3. Kalmij S. et al. Polyunsaturated Fatty Acids, Antioxidants, and Cognitive Function in Very Old Men. American Journal of Epidemiology Vol. 145. No 1 pp 33-41.
  4. Hamazaki T et al. Administration of Docosahexaenoic Acid Infulences Behaviour of Plasma Catecholamine Levels at Times of Psychological Stress. Lipids, Vol. 34, Suppl. (1999)
  5. De Lorgeril et al. Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart diseases. Lancet, 1994, vol. 343, 1454-1459.
  6. Renaud S, et al. Cretan Mediterranean diet for prevention of coronary heart disease. American Society for Clinical Nutrition. 1995, 61(Supplement) 1360S-7S.
  7. Jacob R. et al. Prolongation of life span in hypertensive rats by dietary interventions. Effects of garlic and linseed oil. Basic Research in Cardiology 92(4):223-232, 1997
  8. Cunnane SC, et al. Nutritional attributes of traditional flaxseed in healthy young adults. American Journal of Clinical Nutrition. 1995 January, 61(1):62-68.
  9. Bierenbaum ML, et al. Reducing atherogenic risk in hyperlipemic humans with flax seedsupplementation: a preliminary report. Journal of the American College of Nutrition. 1993 October, 12(5):501-4.
  10. Blackburn GL. Nutrition and inflammatory events: highly unsaturated fatty acids (omega-3 vs omega-6) in surgical injury. Proceedings of the Society for Experimental Biology and Medicine. 1992, 200:183-188.
  11. Parbtani A and Clark WF. In: Flaxseed in Human Nutrition.  Cunnane SC and Thompson LU, eds.  Champaign, IL: AOCS Press, 1995, pp. 244-260.
  12. Clark WF, et al. Flaxseed: a Potential Treatment for Lupus Nephritis. Kidney International. 1995 August, 48(2):475-80
  13. Calder P. Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Brazillian journal of Medical and Biological Research. 1998, vol 31(4), 467-90.
  14. Yan L. et al. Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice. Cancer Letters. 1998 124(2): 181-6.
  15. Onogi N. et al. Suppressing effect of perilla oil on azoxymethane-induced foci of colonic aberrant crypts in rats. Carcinogenesis, 17(6): 1291-6, 1996.
  16. Begin ME et al. Selective killing of human cancer cells by polyunsaturated fatty acids. Prostaglandins.1985, vol 19, 177-186
  17. Begin ME et al. Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids. Journal of the National Cancer Institute. 1986, vol 77, 1053-1-61.
  18. Kokoglu et al. Profiles of the fatty acids in the plasma membrane of human brain tumors. Cancer Biochemistry Biophysics, 16(4):301-12 1998
  19. Thompson LU. Flaxseed and its lignan and oil components reduce mammary tumor growth at late stage of carcinogenesis. Carcinogenesis, 17(6): 1373-6 1996.
  20. Christophe A at al. Intake of Alpha Linolenic Acid, but not of Docosahexaenoic Acid, correlates positively with DHA content, and with parameters for fertilization potential of human spermatozoa. Abstract for 90th AOCS Annual Meeting, Orlando, Florida 1999
  21. Hamadeh MJ, et al. Nutritional aspects of flaxseed in the human diet. Proceedings of the Flax Institute.  1992, 4:48-53.

Let’s Work Together


Please refer to our Privacy Policy for further information on the processing of personal data.